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block-system block-system-main-block no-title"> <div class="content block-content"> <!-- Start Display article for teaser page --> <!-- Start Display article for detail page --> <article data-history-node-id="1190" about="/index.php/articles/news/international-journal-molecular-sciences-publication" typeof="schema:Article" class="node node-detail node--type-article node--promoted node--view-mode-full clearfix"> <div class="post-block"> <div class="post-thumbnail post-standard"> <div class="field field--name-field-image field--type-image field--label-hidden field__item"> <div class="item"> <img property="schema:image" loading="lazy" src="/sites/pathology/files/styles/announcements/public/articles/International%20Journal%20of%20Molecular%20Sciences%20Publication_2025-10-27.png?itok=Ls6szCSH" alt="Asia Boyd International Journal of Molecular Sciences Publication" typeof="foaf:Image" class="image-style-announcements" /> </div> </div> </div> <div class="post-content"> <h1 class="post-title"><span property="schema:name" class="field field--name-title field--type-string field--label-hidden">International Journal of Molecular Sciences Publication</span> </h1> <span property="schema:name" content="International Journal of Molecular Sciences Publication" class="rdf-meta hidden"></span> <span property="schema:interactionCount" content="UserComments:0" class="rdf-meta hidden"></span> <div class="post-meta"> <span class="post-categories"> <div class="field field--name-field-post-category field--type-entity-reference field--label-hidden field__item"><a href="/index.php/articles/news" hreflang="en">News</a></div> </span> | <span class="post-created"> 27 October 2025 </span> </div> </div> <div class="node__content clearfix"> <div property="schema:text" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Congratulations to Asia-Lily Boyd for her recent publication in the <em>International Journal of Molecular Sciences</em>. </p> <p><span><span><span><span><span><span><span><span><span>Triple-negative breast cancer is an aggressive disease with limited treatment options and poor prognosis. Although immune checkpoint inhibitors targeting the PD-1/PD-L1 axis have shown clinical promise, many TNBC patients exhibit resistance or limited response, underscoring the need to understand regulatory mechanisms of PD-L1 expression. </span></span></span></span></span></span></span></span></span></p> <p><span><span><span><span><span><span><span><span><span>Department of Pathology & Molecular Medicine PhD candidate Asia-Lily Boyd and her colleagues Prem Khanal, Tynan Kelly, Anni Ge and Yawei Hao in Dr. Xiaolong Yang’s group now report in the </span></span></span></span><span><span><span><span><em><a href="https://www.mdpi.com/1422-0067/26/20/10108">International Journal of Molecular Sciences </a></em></span></span></span></span><span><span><span><span>that focal adhesion kinase promotes the ability of PD-L1 to reduce T-cell-mediated cancer cell killing. These findings suggest that currently available and clinically approved inhibitors of the focal adhesion kinase could enhance the therapeutic benefits of PD-L1 blockade in the treatment of triple-negative breast cancer patients. </span></span></span></span></span></span></span></span></span></p> <p><span><span><span><span>Congratulations to Asia-Lily on this exciting first author publication! Read her published work here: </span></span></span></span><a href="https://www.mdpi.com/1422-0067/26/20/10108">Kinome-Wide Screening Identifies FAK as a Novel Post-Translational Regulator of PD-L1 Stability and Immune Evasion in Triple-Negative Breast Cancer</a></p> </div> </div> <div id="node-single-comment"> </div> </div> </article> <!-- End Display article for detail page --> </div> </div> </div> </div> </div> </div> <!-- Sidebar Left --> <!-- End Sidebar Left --> <!-- Sidebar Right --> <div class="col-lg-4 col-md-4 col-sm-12 col-xs-12 sidebar sidebar-right theiaStickySidebar"> <div class="sidebar-inner"> <div class="region region-sidebar-right"> <div class="views-element-container block block-views block-views-blockpost-other-block-1" id="block-gavias-financial-views-block-post-other-block-1"> <h2 class="block-title" ><span>Recent Posts</span></h2> <div class="content block-content"> <div><div class="post-style-list gva-view view view-post-other view-id-post_other 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