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</div> </div> </div> </div> </div> </div> </header> <div class="breadcrumbs"> <div class="region region-breadcrumbs"> <div class="breadcrumb-content-inner"> <div class="gva-breadcrumb-content"> <div id="block-gavias-financial-breadcrumbs" class="text-dark block gva-block-breadcrumb hidden-xs block-system block-system-breadcrumb-block no-title"> <div class="container"> <div class="breadcrumb-content-main"> <h2 class="page-title hide">Blog </h2> <div class="hidden-breadcrumb-links"> <div class="content block-content"> <div class="breadcrumb-links"> <div class="content-inner"> <nav class="breadcrumb " role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> <span class=""> / </span> </li> <li> <a href="/articles">Articles</a> <span class=""> / </span> </li> <li> <a href="/articles/news">News</a> <span class=""> / </span> </li> <li> </li> <li> Comprehensive profiling of clinical approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing </li> <li></li> </ol> </nav> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div role="main" class="main main-page"> <div class="clearfix"></div> <div class="clearfix"></div> <div class="clearfix"></div> <div id="content" class="content content-full"> <div class="container"> <div class="content-main-inner"> <div class="row"> <div id="page-main-content" class="main-content col-xs-12 col-md-8 sb-r "> <div class="main-content-inner"> <div class="content-main"> <div class="region region-content"> <div id="block-gavias-financial-content" class="block block-system block-system-main-block no-title"> <div class="content block-content"> <!-- Start Display article for teaser page --> <!-- Start Display article for detail page --> <article data-history-node-id="1213" about="/articles/news/comprehensive-profiling-clinical-approved-kinase-inhibitors-reveals-mutation-specific" typeof="schema:Article" class="node node-detail node--type-article node--promoted node--view-mode-full clearfix"> <div class="post-block"> <div class="post-thumbnail post-standard"> <div class="field field--name-field-image field--type-image field--label-hidden field__item"> <div class="item"> <img property="schema:image" loading="lazy" src="/sites/pathology/files/styles/announcements/public/articles/Taran%20Gujral%20no%20text.jpg?itok=1dpQIZrV" alt="Former DPMM PhD " typeof="foaf:Image" class="image-style-announcements" /> </div> </div> </div> <div class="post-content"> <h1 class="post-title"><span property="schema:name" class="field field--name-title field--type-string field--label-hidden">Comprehensive profiling of clinical approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing</span> </h1> <span property="schema:name" content="Comprehensive profiling of clinical approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing" class="rdf-meta hidden"></span> <span property="schema:interactionCount" content="UserComments:0" class="rdf-meta hidden"></span> <div class="post-meta"> <span class="post-categories"> <div class="field field--name-field-post-category field--type-entity-reference field--label-hidden field__item"><a href="/articles/news" hreflang="en">News</a></div> </span> | <span class="post-created"> 13 May 2026 </span> </div> </div> <div class="node__content clearfix"> <div property="schema:text" class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>This publication in <span><span><span><span><em>Nature Biotechnology </em></span></span></span></span>can be viewed <a href="https://www.nature.com/articles/s41587-026-03090-8 ">here</a></p> <p><span><span><span><span><span><span><span><span><span>Former DPMM PhD student and now Professor at the Fred Hutch Cancer Center at the University of Washington Dr. Taranjit Gujral has just published in </span></span></span></span><span><span><span><span><em>Nature Biotechnology </em></span></span></span></span><span><span><span><span>a paper entitled</span></span></span></span><span><span><span><span><em> “Comprehensive profiling of clinical approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing”. </em></span></span></span></span><span><span><span><span>This study provides us with a powerful resource to identify approved drugs to target oncogenic kinases in cancer. Taran has also generated a user-friendly web site called </span></span></span></span><span><span><span><span>KIRHub</span></span></span></span><span><span><span><span> that allows us to profile kinases and select effective inhibitors (</span></span></span></span><span><span><span><span><a href="https://kirhub.fredhutch.org/">https://kirhub.fredhutch.org/</a></span></span></span></span><span><span><span><span>). Taran is also </span></span></span></span><span><span><span><span><a href="https://careers-fhcrc.icims.com/jobs/31048/post-doctoral-research-fellow---systems-biology/job?mobile=false&width=1193&height=500&bga=true&needsRedirect=false&jan1offset=-300&jun1offset=-240">recruiting post-docs </a></span></span></span></span><span><span><span><span>if you’re looking! </span></span></span></span><span><span><span><span><a href="https://research.fredhutch.org/gujral/en.html">https://research.fredhutch.org/gujral/en.html</a></span></span></span></span> </span></span></span></span></span></p> <p>The Gujral Lab is seeking a highly motivated and innovative <strong>Post-Doctoral Research Fellow</strong> to advance precision oncology through systems biology approaches that integrate functional screening, genomics, and computational modeling.</p> </div> </div> <div id="node-single-comment"> </div> </div> </article> <!-- End Display article for detail page --> </div> </div> </div> </div> </div> </div> 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