Nathan Kaufman was born in Lachine, Quebec and educated at McGill University, graduating with a medical degree in 1941. He interned at the Royal Victoria Hospital and then served as a Medical Officer to a tank battalion in Western Europe and was honoured with a MBE. After 18 months as a pathology resident at the Jewish General in Montreal he moved with his wife Rita to the Cleveland Metropolitan General Hospital to complete his residency. He then joined the Faculty at Case Western and embarked on a successful career in iron metabolism research, medical education and laboratory administration. In 1967, after 7 years as a Professor at Duke University, he was recruited by Dean Harry Botterell to succeed Bob More as the Head of Pathology at Queen's.